COMMON BRAND NAME (S): Wellbutrin
Feb 1, 2024 · Bupropion may cause some people to be agitated, irritable, or display other abnormal behaviors
The incidence of seizures increases dramatically at higher dosages
Objective: To examine in children and adolescents the 24-hour, steady-state clinical pharmacokinetics of an extended-release (XL) formulation of bupropion (Wellbutrin XL)
All patients being treated with bupropion for smoking cessation treatment should be observed for neuropsychiatric symptoms including changes in behavior, hostility
Conclusions: The preclinical and clinical data show that bupropion acts via dual inhibition of norepinephrine and dopamine reuptake and is devoid of clinically
Bupropion hydrochloride, a noradrenergic/dopaminergic
Bupropion is a dopamine and norepinephrine reuptake inhibitor, which is indicated for the treatment of major depressive disorder and for smoking cessation
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Bupropion (also known as the brand name product Wellbutrin ®) is a norepinephrine / dopamine -reuptake inhibitor (NDRI) used most commonly for the management of Major
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Steady-state plasma and urine bupropion disposition was markedly stereoselective, with up to 40-fold differences in plasma concentrations of the active metabolite S,S
Design:
It is also used as part of a support program to help people stop smoking
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The maximum recommended dosage of Wellbutrin SR is 200 mg twice per day
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Oral absorption approaches 100%, and the volume of distribution is 19 l/kg at steady state
Bupropion and its metabolites exhibit linear kinetics following chronic administration of 300 to 450 mg/day
3 All antidepressants can cause anxiety, and they do in about 1 in 10 depressed patients
Bupropion Pregnancy Warnings
Comments: WELLBUTRIN SR Tablets 150 mg twice daily to the immediate-release formulation of bupropion at 100 mg 3 times daily, peak plasma concentrations of bupropion at steady state for WELLBUTRIN SR Tablets were approximately 85% of those achieved with the immediate-release formulation
Methodologically more robust trials support The antidepressant bupropion is stereoselectively metabolized and metabolite enantiomers have differential pharmacologic effects, but steady-state enantiomeric disposition is unknown
Brand names of bupropion include Aplenzin®, Forfivo®, and Wellbutrin®
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In this case, the recommended starting dose of Wellbutrin XL is 150 mg frequent need to urinate
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Bupropion is a chiral, basic, highly lipophilic drug, clinically used as racemate that undergoes extensive stereoselective metabolism