Tizanidine and hypotension

Stroke patients have multiple co-morbidities such as hypertension, diabetes, and seizure. The authors present a 10-year-old boy chronically treated with lisinopril, an angiotensin converting enzyme inhibitor, to control hypertension who developed hypotension following the addition of tizanidine, an alpha-2 agonist, for the treatment of spasticity

2024-03-29
    Picture of lamotrigine
  1. 60, p=0
  2. loss of consciousness
  3. 5 WARNINGS AND PRECAUTIONS 5
  4. Epub 2019 Sep 18
  5. It is also used off-label for insomnia and anxiety
  6. The presentation is often with hyperadrenergic symptoms
  7. 1345/aph
  8. Hypotensive effect is dose related
  9. pale or blue lips, fingernails, or skin
  10. Syncope has been reported in the post marketing setting
  11. 125
  12. Clinically Significant Bradycardia From Tizanidine
  13. Syncope has been reported in the post marketing setting
  14. 5
  15. Syncope has been reported in the post marketing setting
  16. Tizanidine is an α2-adrenergic agonist that can produce hypotension
  17. However, both drugs are broadly utilized in various countries
  18. Most of the patients were female (n = 59, 64
  19. 5
  20. doi:
  21. Epub 2019 Sep 18
  22. 1, 7
  23. Tizanidine is an α2-adrenergic agonist that can produce hypotension
  24. 002)