Abstract—Hydrochlorothiazide (HCTZ) has often been contrasted with chlorthalidone, but relatively little is known about HCTZ versus indapamide (INDAP)
The purpose of this review is to update the published data on the efficacy and safety of HCTZ, chlorthalidone, and indapamide as add-on therapy in patients with
However, thiazide-like diuretics (ie, chlorthalidone, indapamide) are preferred over thiazide-type diuretics (eg, hydrochlorothiazide), and there are only two
Clinical tolerability was better
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This lowers the amount of fluid flowing through the veins and arteries
The long‐acting nature of chlorthalidone results in better control (1
Long-term discontinuation of hydrochlorothiazide may not be necessary in patients with thiazide-associated hypercalcemia
The method utilizes proteins precipitation with acetonitrile as only sample
Thiazides, a reliable class of antihypertensive diuretics for over 60 years,[1] have
Three thiazide diuretics are the most commonly used: hydrochlorothiazide (HCTZ), chlorthalidone, and
Athanassiadis and colleagues8 reported on 40 patients in each group taking either indapamide alone, indapamide and captopril, or indapamide and propranolol for 4 months
A: In the use of medicines, the issue is not which drug is better than the other but which one is more appropriate in a specific case
Hyperuricemia is a relatively common finding in people treated with a loop or thiazide diuretic and may, over a period of time, contribute to new-onset gout or recurrence of established gout []
The DCP and EVIDENCE trial results, when available, may shed important light on this
Objective: The primary purpose of this study was to evaluate instituting nighttime dosing to control hypertension and compare the short-term effectiveness of blood pressure control with indapamide versus hydrochlorothiazide
Little research has been performed on sulfonamide antibiotic and sulfonamide diuretic allergic cross-reactivity
Twelve trials were identified: five based on the comparison of indapamide versus hydrochlorothiazide and seven based on the chlorthalidone versus hydrochlorothiazide