Orlistat works by keeping your intestines from absorbing some of the fats from the food that you eat
Orlistat taken at a dose of 120mg thrice a day results in 200 Calorie deficit per day
The XENDOS study showed reductions in all fat soluble vitamins except vitamin D
It can keep your body from absorbing fat-soluble vitamins
Orlistat blocks the work of lipase
Drug interactions, dosage, and pregnancy and breastfeeding safety are provided
Orlistat binds to the gastric and pancreatic lipase enzymes in the stomach and small intestine so they cannot bind to fat molecules and break them down
Conclusion
Looking outside of drug interactions, there are concerns that several drugs could affect vitamin D levels in other ways Orlistat for weight loss is available via a private service from your local pharmacist
Reported side effects of eating too much fat Fat-soluble vitamins — the absorption of vitamins A, D, E, K, and beta-carotene may be impaired in people taking orlistat; however, in most people levels remain within the normal range
The Blocking pancreatic lipase will, in turn,, block the chemical digestion and absorption of lipids, potentially leading to weight loss
Underactive thyroid—Use with caution
Mechanism
Study objectives: To determine whether orlistat causes fat-soluble vitamin deficiencies in African-American and Caucasian adolescents
The baseline data, therefore, reflects their beliefs and experiences at the start of their course of taking orlistat but does not reflect that, either before or at the very start of this process
Management: Administer oral fat soluble vitamins at least 2 hours before or after the administration of orlistat
This medicine must be used together with a reduced-calorie diet
Since Alli is half the dose, it only blocks about 25% of the fat you eat (unlike Xenical which blocks about 30%)