Before you take DILANTIN, inform your doctor or pharmacist of all the medications you take, including prescription and over-the-counter medicines, and any medical conditions you have, including if you: Have kidney or liver problems as you may show early signs of toxicity
My daughter (21 years) has been on dilantin for 2 years, but the doseage has increased due to tonic clonics
Liver fibrosis results from chronic damage to the liver due to the excessive accumulation of extracellular matrix proteins that occurs in most types of chronic liver
Dilantin is a medicine used to prevent seizures
Get medical help right away if you have any very serious side effects, including: uncontrolled muscle movements, signs of liver problems (such as nausea/vomiting that doesn't stop
Hepatotoxicity is a
Indeed, several commonly used anticonvulsants (phenytoin, valproate, carbamazepine) are consistently ranked in the top causes of clinically apparent drug induced liver injury and are frequently listed in
Treating and managing your liver disease early can help limit this damage
2) DILANTIN is available as 30 mg and 100 mg extended phenytoin sodium capsules
It is useful for the prevention of tonic-clonic seizures (also known as grand mal seizures) and focal seizures, but not absence seizures
Liver problems
Significant increases, such as those more than three times the upper limit of normal (ULN) or Liver cirrhosis can lead to a decrease in serum albumin as well as a decreased metabolism of phenytoin by the CYP450 pathway, both leading to increased amounts of free phenytoin in the serum
nausea
(Among 899 cases of drug induced liver injury enrolled in a US prospective study between 2004 and 2013, 40 [4
liver disease (including liver disease caused by past phenytoin use) lupus; folate or vitamin B-12 deficiency (megaloblastic anemia) This drug may make you dizzy or drowsy
Your blood sugar level can be altered while taking DILANTIN; If you take DILANTIN during pregnancy, your baby is at risk for serious birth defects and bleeding problems right after birth Liver damage and dilantin ; Community Forum Archive
In addition, forum questions and responses include information and content that has been generated by Phenytoin is an anticonvulsant drug, related to the barbiturates in chemical structure, but has with a history of renal or liver disease should not receive the oral loading dose regimen
Liver test abnormalities with ALT elevations above 3 times the upper limit of normal have been reported to occur in ~1% of patients on duloxetine, but elevations were usually self-limited and did not require dose modification or discontinuation
Idiosyncratic drug-induced liver injury (DILI) is an important cause of morbidity and mortality following drugs taken in therapeutic doses
Lamotrigine (la moe' tri jeen) is a phenyltriazine and belongs to an anticonvulsant class of its own
hepatitis E
Renal or hepatic disease can prolong the elimination of the parent drug or an active metabolite leading to accumulation and clinical toxicity