ABSTRACT: Acute mountain sickness (AMS) is a common disorder, affecting patients who travel to areas of high altitude
Acetazolamide is also used to reduce the severity and duration of symptoms (upset stomach, headache, shortness of breath, dizziness, drowsiness, and fatigue) of altitude (mountain) sickness
Acute mountain sickness (AMS) is a form of altitude sickness caused by ascent to high altitude (>2500m) before there is adequate time for acclimatisation
Its mechanism is via inhibition of the carbonic anhydrase enzyme which
The objective of this study was to evaluate the efficacy of day of ascent dosing of acetazolamide for AMS prevention
Symptoms are similar to those of the flu and include headache, nausea and fatigue
A steroid medication called dexamethasone may be an alternative
To date, the only dose studied for treatment is 250 mg (2 doses taken 8 hours apart), although the lower dosage used for prevention has anecdotally been successful
Search PubMed; Vardy J
Learn about mountain sickness and how to use diamo to prevent or lessen its symptoms
The RADICAL Trial was a prospective, double-blind, randomized, non-inferiority trial evaluating reduced dose (62
1 mg/(kg/m 2)/d, with similar results as weight-based outcomes for both acute mountain sickness and moderate acute mountain sickness
33 For all analyses except where the impact of acetazolamide dose was being examined, the two active treatment groups in this trial were pooled into one group
Diamox (acetazolamide) is a medication used most commonly to treat glaucoma, epilepsy, and idiopathic intracranial hypertension , a condition of increased pressure around your brain without a known cause