Instructions Determine the appropriate dose for the body weight of the mare based on the dosing table below
Domperidone
Domperidone, sold under the brand name Motilium among others, is a dopamine antagonist medication which is used to treat nausea and vomiting and certain
Domperidone is an anti-nausea medication
1 mg/kg, PO, q 12 to 24h Dopamine antagonist; stimulation of lactation (agalactia) in postpartum mares, induction of lactation
EQUIDONE (domperidone) gel
, Citation 2016)
Side effects such as feeling drowsy, nervous, agitated or irritable or having a fit are more likely to happen in children
A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic
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For oral use in horses only
5 mg/kg BW; (c) domperidone solution administered intravenously (IV) at 0
Refer to the prescribing information for complete details
Your choice
The safety of domperidone in lactating women and their nursing children has not been evaluated
Ten mL of gelling solution was added into the 900 mL of 0
Domperidone (BCS II) has been chosen for gastric retention as it has a poor oral bioavailability (around 15%), a short biological half-life, and pH-dependent solubility with poor solubility at a high pH and good solubility at low pH
Domperidone is a D2 dopamine receptor antagonist
Chemically, domperidone is 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one
Syringes are supplied in single carton and six per carton
Each cc of gel contains 110 mg of Domelong P (Domperidone)
Another research developed emulsion gel buoyant beads [35], but it could sustain the release of domperidone for 3 h only